R & D

Research and Development

At its core HaemokinesisÂŽ is a Research and Innovation driven company. New Science and how it can lead to better patient outcomes is our core value. In conjunction with Monash University BioPria, Haemokinesis has spent the last 10 years researching and developing a unique blend of new age technology to enhance Immunohaematology testing and Emergency Medicine. We list here all the papers, posters and ARC Linkage grants we have been involved with, if you want to know more or think we may be interested in your work feel free to contact us on [email protected]

 

List of Publications Biosensors

A]- Linked to Haemokinesis ARC LP Partnership

  1. Hertaeg, M,;McLiesh, H;, Tabor, R. and Garnier, G. “A Rapid Paper-Based Blood Typing Method from Droplet Wicking”, 146, 1048-1056 (2021)
  2. Bialkower, Marek and Garnier, Gil, “Fibrinogen Diagnostics in Major Haemorrhage”, Critical Reviews in Analytical Chemistry, 1-16, (2020).
  3. Hertaeg, M.J., Tabor, R.F., Berry, Joseph and Garnier, G., “Radial wicking of biological fluids in paper”, Langmuir, 36 (28) 8209-8217 (2020).
  4. Bialkower, M., Manderson, C., McLiesh, H. and Garnier, G., “Paper Diagnostic for Direct Measurement of Fibrinogen Concentration in Whole Blood”, ACS Sensor, 5 (11) 3627-3638 (2020).
  5. Bialkower, Marek; McLiesh, Heather; Manderson, Clare; Tabor, Rico, F and Garnier, Gil, “ Rapid, Handheld Paper Diagnostic for Measuring Fibrinogen Concentration in Blood”, Analytica Chemica  Acta, 1102, pp72-83 (2020).
  6. Manderson, Clare, A.; McLiesh, Heathe; Curvello, Rodrigo; Tabor, Rico, F. and Garnier, Gil, “Laser-incubated Immunohaematology”, Scientific Reports, 9(July 22th) (2019). P3 Article in the Herald Sun Sept 20; interview 693AM; article Renter in Health section.
  7. Bialkower, Marek; McLiesh, Heather; Manderson, Clare, A.; Tabor, Rico, F and Garnier, Gil, “Rapid Paper Diagnostic for Plasma Fibrinogen Concentration”, Analyst, 144 (16), pp4849-4857 (2019).
  8. Rodrigo Curvello, Llyza Mendoza, Heather McLiesh, Jim Manolios, Rico F. Tabor and Gil Garnier, “Nanocellulose Hydrogel for Blood Typing Diagnostics”, ACS BioMaterials, 2 (6) 2355-2364 (2019).
  9. Curvello, Rodrigo; Raguwanshi, Vikram and Garnier, Gil, “Perspectives on Nanocellulose Hydrogels for Biomedical Applications”, Advances in Colloid and Interfacial Science, vol 8;267: pp 47-61 (2019).
  10. Guillaume Garnier, Clare Henderson, Saveen Giri and Gil Garnier, “IdentiCyte: Simple Red Blood Cell Identification Software “Software X, 9, pp223-229, (2019).
  11. Hertaeg, M.J., Tabor, R.F., Berry, Joseph and Garnier, G., “Dynamics of stain growth from sessile droplets on paper”, JCIS, 541, pp. 312-321 (2019).
  12. Hertaeg, M.J., Tabor, R.F. and Garnier, G., “Effect of protein adsorption on the radial wicking of blood droplets in paper”, JCIS, Vol 528, pp116-123 (2018).
  13. Henderson, C., McLiesh, H., Then, W.L. and Garnier, G., “Activity and Longevity of antibody in paper-based blood typing diagnostics”, Frontiers in Chemical Engineering, “Sensing MY Biosphere” special topic, Vol 6, article 193, May (2018).
  14. Huang, W., Gengenbach, T., Tian, J., Shen, W. and Garnier, G., “Effect of Bovine Serum Albumin Treatment on the Aging and Activity of Antibodies in Paper Diagnostics”, Frontiers in Chemical Engineering, “Sensing MY Biosphere” special topic, volume 6, article 161 (2018).
  15. Huang, Z., Gengenbach, J. Tian, W. Shen and Garnier, G, “The Role of Polyaminoamide-epichlorohydrin (PAE) on Antibody Longevity in Bioactive Paper”, Colloids and Surfaces: B, 158,197-202 (2017).
  16. Huang, Z., Raghuwanshi, V., and Garnier, G., “Functionality of IgG and IgM antibodies physisorbed on cellulosic films: effect of aging and surface chemical composition”, Frontiers in Biochemical Engineering, 5,41 (June 29th)
  17. Yeow, N., Tabor, R.F. and Garnier,” Atomic Force Microscopy for Red Blood Cells: From reb blood cell to Immunohaematology”, Advances in Colloids and Interface Science, special Edition, Recent nanotechnology and colloid science development for Biomedical applications, 249 pp 149-162 (2017).
  18. Yeow, N., Tabor, R.F. and Garnier, G., “Direct measurement of IgM- antigen interaction energy on individual red blood cells”, Colloids and Surfaces: B, 155, 373-378 (2017).
  19. Then, W.L., Aguilar, M and Garnier, G., “Quantitative detection of weak D antigen variant in blood using SPR”, Scientific Report, 7 (1) 1616 (2017).
  20. Yeow, N., Tabor, R.F. and Garnier, G., “Mapping the distribution of antigen-antibody interaction forces on individual red blood cells”, Scientific Report, 7, 41956 (2017).
  21. Then, W.L., McLiesh, H., Aguilar, M and Garnier, G., “Duffy Blood Group (Fya & Fyb) Analysis using surface plasmon resonance”, Biomedical Microdevices, 18 (6), p-101 (2016).
  22. Yeow, L., McLiesh, H., N., Guan, L., Shen, W. and Garnier, G. “Paper-Based Assay for Red Blood Cell Antigen Typing by Indirect Antiglobulin Test”, Analytical Biochemistry, Vol 408 19, 5231-5231(2016).
  23. McLiesh, H., Sharman, S. and Garnier, G,“ Effect of Cationic Polyelectrolytes on the Performance of Paper Diagnostics for Blood Typing”, Colloids and Surface B: Biointerfaces,  133, pp189-197 (2015).
  24. Then, W.L., M. Aguilar, and G. Garnier “Quantitative blood typing using Surface Plasmon Resonance”, Biosensors and Bioelectronics, 73, 79-84 (2015).
  25. Yeow, N., McLiesh, H. and Garnier, G., “Indirect Antiglobulin Paper Test for Red Blood Cell Antigen Typing by Flow-through Method “, Analytical Methods, 7, 4645-4649 (2015).
  26. Zhang,L, Li, X; Ong, L, Tabor, R., Bowen, B., Fernando, A., Nilghaza, , Garnier, G., Gras, S.,  Wang, X., Shen, W. “Cellulose nanofibre textured SERS substrate”, Colloids and Surfaces A, 468, 309-314, (2015).
  27. Then, W.L., LI, M., McLiesh, H, Shen, W. and Garnier, G., “The detection of blood group phenotypes using paper diagnostics”, Vox Sanginis, 108, (2), 186-196 (2015). DOI: 10.1111/vox.12195.
  28. Ballerini, D.R., Ngo, Y.H., Garnier, G., Ladewig, B.P., Shen, W., Jarujamus, P., “ Gold nanoparticle-functionalized thread as a substrate for SERS study of analytes both bound and unbound”, AIChE Journal 60,(5) 1598-1605 (2014).
  29. Guan, Liyun; Cao, Rong; Tian, Junfei; McLiesh, Heather; Garnier, Gil; Shen, Wei, “A preliminary study on the stabilization of blood typing antibodies sorbed into paper”, Cellulose, 21(1), 717-727, (2014).
  30. Then, W.L. and Garnier, G. “Paper microfluidics: applications and perspectives”, in 15th Fundamental Research Symposium, L’Anson, S., Ed., Cambridge Vol. 2 pp. 541-584 (2013).
  31. Then, W.L. and Garnier, G., “Paper Diagnostics in Biomedicine”, Reviews in Analytical Chemistry. Volume 32, Issue 4, Pages 269–294, ISSN (Online) 2191-0189, ISSN (Print) 0793-0135, DOI: 1515/revac-2013-0007, September 2013.
  32. Al-Tamimi, M., Shen, W., Rania, Z., Huy, T. and Garnier, G., “Validation of paper-based assay for rapid blood typing”, Analytical Chemistry, 84(3), 1661–1668, (2012).

 

B]- Independent studies

  1. Hertaeg, Michael.; Kesarwani, Vidhi.; Leguizamon, S.; McLiesh, Walker, Julia; Corrie, Simon,and Garnier, Gil “Wash-free Paper Diagnostics for the Rapid Detection of Blood Type Antibodies”, Analyst (accepted) September15th (2021).
  2. Hertaeg, Michael; Tabor, Rico; Routh, Alex and Garnier, Gil, “Pattern Formation in Blood Drops”, Philosophical Transactions A, The Royal Society Publishing (in press), February12 (2021).
  3. Hertaeg, M.; Rees-Zimmerman C.; Routh, A;, Tabor, R. and Garnier, G. “ Predicting coffee ring formation upon drying in droplets of particle suspensions”, JCIS, 591, pp 52-57 (2021).
  4. Alves de Sousa, D.; Curvello, R.; Henderson, E.; Kesarwani, V.; Leguizamon, S.; McLiesh, H.; Raguwanshi, V.; Samadian, H.; Wood, E.; McQuilten, Z., Graham, M.; Wieringa, M.; Banaszak Holl, M., Garnier, G. and Corrie, S., “ Rapid gel-card agglutination assays for serological analysis following COVID-19 infection in humans”, ACS Sensors, 5 (8), 2596-2603 (2020).
  5. Raghuwanshi, Vikram; Yu, Branden and Garnier, G,” Reversible pH Responsive Bovine Serum Albumin Hydrogel Sponge Layer”, Frontiers in Bioengineering and Biotechnology, section Nanobiotechnology, 8, 573 (2020).
  6. Raguwanshi, Vikram, and Garnier, Gil, “Characterization of Hydrogels: Linking the nano to the microscale”, Advance Colloids and Interface, 102044 (2019).
  7. Raguwanshi, Vikram, and Garnier, Gil, “Cellulose Nano-Films as Bio-Interfaces” Frontiers in Chemistry, special topics on “thin films”, 7, p 535 (2019).
  8. Llyza Mendoza, Thilina Gunawardhana, Warren Batchelor and Gil Garnier, “Nanocellulose for Gel Electrophoresis”, JCIS, 540, pp148-154 (2019).
  9. Prathapan, R., McLiesh, H., Garnier, G., and Tabor, R.F, “Surface engineering of transparent cellulose nanocrystal coatings for biomedical applications”, ACS Applied Bio materials, 1 (3) 727-737, (2018).
  10. Raghuwanshi, V., Su, J., Raverty, Garvey, C., W., Holt, S., Holden, P, Gillon, M., Batchelor, W. and Garnier, G., “Visualization and Quantification of IgG Antibody adsorbed at the cellulose-liquid interface”, Biomacromolecules, 18 (8) 2439-2445 (2017).
  11. Tiwari, S., Garnier, G. and Rao, V.R., “One dimensional zinc oxide nanostructures assisted paper-based blood-plasma separation”, Vacuum, 146, 586-591 (2017).
  12. Raghuwansi,V., Huang, Z., Garvey, W., Batchelor, W. and Garnier, G., “ Biomacromolecule adsorption at the cellulose liquid-interface”, 7th Fundamental Research Symposium series- Paper Physics, Oxford September (2017).
  13. Tiwari, S., Vinchurkar, R.M.V. Rao and Garnier, G., “Zinc Oxide Nanorod functionalized paper for protein pre-concentration”, Scientific Reports, 7, 43905 (2017).
  14. Garvey, C., J., Khan, M.S., Weir, M.P. and Garnier, G.,” Localisation of Alkaline Phosphatase in the Pore Structure of Paper”, Colloids and Polymer Science, 295 (8), pp1-12 (2017).
  15. Raghuwanshi, V., Su, J., Raverty, Garvey, C., W., Holt, S., Holden, P, Gillon, M., Batchelor, W. and Garnier, G., “Bio-deuterated cellulose thin films for enhanced contrast in neutron reflectometry”, Cellulose, Vol 24, No 1, pp 11-20, (2017).
  16. Su, J., Raghuwanshi, V., Raverty, W., Garvey, C., Holden, P, Gillon, M., Holt, S., Tabor, R., Batchelor, W. and Garnier, G., “Smooth deuterated cellulose films for the visualization of adsorbed bio-macromolecules”, Scientific Report 6, # 36119, October 31, (2016).
  17. Ngo, Y., Then, W.L, Shen, W. and Garnier, G., ”Gold nanoparticles paper as a SERS Bio-diagnostic Platform” JCIS, 409, pp 59-65 (2013).
  18. Ngo,Y., Li, D., Simon, G. and Garnier, G., “ Formation of polyelectrolyte-gold nanoparticles necklaces on paper”, Journal of Colloids and Interfacial Science, 405, 71-77 (2013).
  19. Ngo, Y.H., Li, D., Simon, G. and Garnier, G, “Effect of Cationic Polyacrylamide Dissolution on the Adsorption State of Gold Nanoparticles on Paper and Their Surface Enhanced Raman Scattering Properties “Colloids and Surfaces: A, 420, 46-52 (2013).
  20. Ngo, Y.H., Li, D., Simon, G. and Garnier, G., “Effect of Cationic Polyacrylamides on the Aggregation and SERS Performance of Gold Nanoparticles-treated Paper”, Journal of Colloid and Interface Science, 392, 237-246 (2013).
  21. Khan, M. and Garnier, G., “Direct measurement of enzymatic kinetics on bioactive paper”, Chemical Engineering Science, 87, 91-99 (2013).
  22. Su, J., Al-Tamimi, M. and Garnier, G. “Engineering paper as a substrate for blood typing bio-diagnostics”, Cellulose, 19 (5) 1749-1758 (2012). DOI: 10.1007/s10570-012-9748-7
  23. Ngo, Y.H., Li, D., Simon, G. and Garnier, G., “Gold nanoparticles-paper as a 3-dimensional SERS substrate”, Langmuir, 28 (23), pp 8782-8790 (2012). IF= 4.186.
  24. Ngo, Y., D. Li, G. Simons and Garnier, G., “Nanoparticle Functionalized paper”, Advances in Colloid and Interface Science, 163, pp 23-38 (2011).
  25. Khan, M.S., Thouas G., Whyte, G., Shen, W and G. Garnier, “Paper diagnostic for instantaneous blood typing”, Analytical Chemistry, 82 (10), p4158-4164 (2010).
  26. M.S., Hannifa, S.B.M., Slater, A. and Garnier, G., “Effect of Polymer on the retention and aging of enzyme on bioactive papers“, Colloids and Surface B, 79 (1) pp 88-96 (Aug 2010).
  27. Xu Li, Junfei Tian, Mohidus Samad Khan, Gil Garnier, Wei Shen, “Fabrication of Paper-based microfluidic sensors by printing”, Colloids and Surface B, 76 (2), pp. 564-570 (April 2010).
  28. Khan, M. S., Fon, D., Li, X., Tian, J., Forsythe, J., Garnier, G., and Shen, W. “Biosurface Engineering Through Ink Jet Printing.”, Colloids and Surfaces B: Biointerfaces, 75, pp 441-447 (2010).
  29. Khan, M. S., Li, X., Shen, W., and Garnier, G. “Thermal Stability of Enzymatic Papers.” Colloids and Surfaces B: Biointerfaces 75, pp. 239-246 (2010).
  30. Khan, M. S., Tian, J., Xu, L., Shen, W., and Garnier, G. (2009), “Bioactive Enzymatic Papers.” 14th Fundamental Research Symposium, “Advances in Pulp and Paper Research, Oxford 2009”. Anne’s College, Oxford, pp. book 2, September 13-18, (2009).

 

C]- PUBLICATION SUBMITTED

  • Manderson, Clare; McLiesh, Heather; Manolios, Jim and Garnier, Gil, “Laser incubation for the rapid detection and typing of red cell alloantibodies in human blood samples”, Transfusion Medicine Reviews, (submitted) August 27th (2021).

 

AWARDS AND DISTINCTIONS

  • 2020 Finalist for the Australian Engineering Excellence Award (AEEA),  Engineers Australia, Gil Garnier and Clare Manderson ” Fast- pre-transfusion blood testing with laser technology”
  • Manderson, Clare, Monash University 2020 Dean’s Award for Excellence in Research by a Research Fellow.
  • Manderson, Clare, McLiesh, Heather, Tabor, Rico, and Garnier, Gil, ‘Pre-transfusion testing using laser incubation ‘, Blood 2019, Annual Sceintific Meeting, Oct 20-23 (2019), Perth, WA, Australia. Award and Prize for best presentation of the conference.
  • Michael Hertaeg (2019), Award and prize best presentation – Biotechnology Section, “Radial wicking in paper for bio-diagnostics”, CEPA conference, October 31st(2019), Monash University.